2-(Chloromethyl)pyrimidine hydrochloride

2-(Chloromethyl)pyrimidine hydrochloride - Names and Identifiers

Name	2-(Chloromethyl)pyrimidine hydrochloride
Synonyms	EOS-62042 2-CHLORO MEHYL PYRIMIDINE HCL 2-(Chloromethyl)pyrimidine hydrochloride 2-(CHLOROMETHYL)PYRIMIDINE HYDROCHLORIDE PyriMidine, 2-(chloroMethyl)-, hydrochloride 2-Chloromethylpyrimidine, HCl salt 2-CMP (HCl salt)
CAS	936643-80-0
EINECS	676-320-5
InChI	InChI:1S/C5H5ClN2.ClH/c6-4-5-7-2-1-3-8-5;/h1-3H,4H2;1H

2-(Chloromethyl)pyrimidine hydrochloride - Physico-chemical Properties

Molecular Formula	C5H5ClN2.ClH
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

2-(Chloromethyl)pyrimidine hydrochloride - Risk and Safety

HS Code

29335990

2-(Chloromethyl)pyrimidine hydrochloride - Introduction

2-(Chloromethyl)pyrimidine hydrochloride is an organic compound with the chemical formula C5H5Cl2N2. HCl. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless to slightly yellow crystalline powder
-melting point: 147-150 ℃
-Solubility: Soluble in alcohol, chloroform, dimethyl sulfoxide and dimethylformamide, insoluble in water

Use:
- 2-(Chloromethyl)pyrimidine hydrochloride are widely used in organic synthesis as precursors of pyrimidine compounds. It can react with other organic compounds to generate anti-tumor drugs, pesticides, dyes and fluorescent probes containing pyrimidine structures.

Method:
- 2-(Chloromethyl)pyrimidine hydrochloride can be prepared by the following steps:
1. In chloroacetonitrile, pyrimidine reacts with trichloromethane-based copper chloride.
2. The product is reacted with hydrochloric acid to give 2-(Chloromethyl)pyrimidine hydrochloride.

Safety Information:
- 2-(Chloromethyl)pyrimidine hydrochloride are organic chlorine compounds, should avoid contact with strong oxidants.
-When using, should wear appropriate protective gloves and glasses, avoid inhalation or contact with skin.
-During operation or storage, maintain a well-ventilated environment.
-If inhaled or exposed, seek medical attention immediately.

Last Update：2024-04-09 02:00:49

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